Summerschool - Biosensing with channels
21-27 Aout 2010 - Berder Island - Brittany - France
Subject of the summerschool
In biological systems, ions and macromolecules are transported across lipid membranes by highly selective nanoscaled protein channels. The study of these transport processes and their imitation in artificial structures, fabricated by chemical synthesis and micro-fabrication, offer many opportunities for applications in ultrasensitive detection of molecules : rapid sequencing of DNA or RNA, studies of conformation (secondary structure of RNA, protein folding), or molecular interaction between proteins or between proteins and nucleic acids. The integration of channels and pores in the nanometer micro-fluidic devices or on deposited lipid bilayers on solid surfaces leads to the creation of new bio-sensors. The techniques of "Patch-clamp on a chip" thus become indispensable in drug screening.
The area attracts many researchers from different disciplines : biologists, physicists, chemists and engineers. Classes are devoted to be accessible to multidisciplinary students. They will be given by internationally recognized speakers. Participating students and postdocs will have the opportunity to present and discuss their own research in poster sessions and student seminars.
The program will include lectures on the following topics :
One half-day will be devoted to presentations by companies working in the field of microfluidics, patch-clamp on a chip, electrophysiology, drug screening and biosensors.
One evening of popularization of the subjects of the school will be organized.
Local Organizing Committee
Loïc Auvray, Philippe Guégan, Laurent Bacri, Jérôme Mathé and Jeanine Tortajada (université d’Évry)
Frank Artzner et Denis Morineau (université de Rennes)
Charlie Gosse (CNRS, LPN)
Chaiman : Mathias Winterhalter (Jakobs University Bremen)
Members : Sergey Bezrukov (NIH, Bethesda), Ulrich Bockelman (ESPCI), Yong Chen (ENS), Cees Dekker (Kavli Institute, Delft), Jacques Gierak (CNRS LPN), Xavier Gidrol (DSV, CEA), Ulrich Keyser (Cavendish Laboratory, Cambridge), Elie Raphaël (ESPCI), Jeanine Tortajada (université d’Évry)
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