JEAN-YVES SALPIN

JEAN-YVES SALPIN

Poste Actuel 

Directeur de Recherche (DR1) CNRS, Institut de Chimie

    Recherche

    Activités de recherche

    • Etude des interactions entre des cations métalliques toxiques et des molécules organiques et biologiques polyfonctionnelles par spectrométrie de masse et calculs quantiques.
    • Thermochimie en phase gazeuse de molécules biologiques
    • Structure d’ions gazeux par spectroscopie infra-rouge de type IRMPD.
    • Modélisation du processus CID

    Outils

    • Spectrométrie de masse : Triple-quadripôle, piège ionique et instrument hybride de type QqTOF ou Orbitrap, équipés de source de type electrospray (ESI) et nano-ESI.
    • Spectroscopie d'action (IRMPD, UVPD) , mobilité ionique
    • Calculs de Chimie Quantique.

    Collaborations

    • Institut Lumière-Matière (ILM) – UMR 5536
    • Laboratoire de Chimie-Physique (LCP) - UMR 8000
    • Institut Louis Lavoisier (ILV) – UMR 8182
    • Ecole Normale Supérieure de Cachan : Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires (LPPSM)- UMR 8531
    • Ecole Nationale Supérieure de Chimie de Rennes – UMR 6226
    • Université Autonoma de Madrid (Espagne)
    • Université de Tunis El Manar (Tunisie)
    • Université « La Sapienza »de Rome (Italie)
    • Memorial University of Newfoundland (Canada)

      Administration de la recherche

      • Directeur du LAMBE
      • Membre du Conseil Scientifique de l'INC
      • Membre du Comité de Pilotage du LabEx Charm3at, coordinateur de l’axe D (Stratégies multi-échelles et sondes multifonctionnelles)
      • Membre du conseil transitoire de la Graduate School (GS) Chimie de l’Université Paris-Saclay
      • Membre du Comité de direction de la fédération de Recherche "Chimie-Physique de Paris Saclay" (FR 3510)
      • Expert scientifique auprès du FNRS (Belgique), FNSNF (Suisse), ANR
      • Membre du comité de programme du TGE FT-ICR
      • Correspondant documentaire auprès de BiblioSciences et Couperin

      Enseignements

      • Cours et Travaux dirigés d’analyse structurale en licence et Master à l’Université d’Evry Val d’Essonne et Université de Paris-Saclay.
      • Enseignement en Formation Permanente.

      Publications


      • A ce jour, l'intégralité de mes publications est parue dans des revues à comité de lecture nécessitant un abonnement payant auprès dans principaux éditeurs de revues scientifiques (Elsevier, Springer, ACS, Wiley, etc...). Dans le contexte du basculement de la politique de publication scientifique vers un modèle open access, et afin de rendre accessible gratuitement à tous les chercheurs mes travaux publiés, j'ai opté à ce jour pour une voie green open access, consistant à déposer sur la base HAL, les manuscrits révisés et acceptés de mes publications. Les documents correspondant aux publications les plus récentes, sont disponibles en cliquant sur les liens [HAL open access]

        To date, all my publications have appeared in peer-reviewed journals requiring a paid subscription from leading publishers of scientific journals (Elsevier, Springer, ACS, Wiley, etc ...). In the context of the switchover from the scientific publication policy towards an open access model, and in order to make my published works available to all researchers free of charge, I have opted for a green open access, by depositing onto the HAL database, the revised and accepted manuscripts of my publications. The documents corresponding to the most recent publications are available by clicking on the links [HAL open access]


         

        2021  


      1. Design and Properties Investigation on a Five-Interaction-based Fluorescent Anion Receptor Clip
        R. Plais, H. Boufroura, G. Gouarin, A. Gaucher, V. Haldys, A. Brosseau, G. Clavier, J-Y. Salpin, D. Prim
        Under preparation


        2020  
      1. Intertwined detection and recognition roles of tetrazine in synergistic anion-π and H-bond based anion receptor.
        R. Plais, G. Gouarin, A. Gaucher, V. Haldys, A. Brosseau, G. Clavier, J-Y. Salpin, D. Prim
        ChemPhysChem 21, 1249-1257 (2020)
        [HAL open access]
        DOI:10.1002/cphc.202000289
      2. Kinetic study of azobenzene E/Z isomerization using ion mobility-mass spectrometry and liquid chromatography-UV detection
        S. Poyer, C. M. Choi, C. Deo, N. Bogliotti, J. Xie, P. Dugourd, F. Chirot, J-Y. Salpin
        Analyst  145, 4012-4020 (2020)
        [HAL open access]
        DOI: 10.1039/D0AN00048E
      3. Insights into Cisplatin Binding to Uracil and Thiouracils from IRMPD Spectroscopy and Tandem Mass Spectrometry
        D. Corinti, M. E.  Crestoni, B. Chiavarino, S. Fornarini, D. Scuderi,  J-Y. Salpin
        Journal of the American Society for Mass Spectrometry  31, 946-960 (2020)
        [HAL open access]
        DOI: 10.1021/jasms.0c00006#
      4. Helically-shaped cation receptor: design, synthesis, characterisation and first application to ion transport
        H. Boufroura, R. Plais, S. Poyer, A. Gaucher, J. Marrot, G. Clavier, F-X. Legrand, C. Huin, P. Guégan, D. Prim, J-Y. Salpin
        RSC Advances  10, 31670-31679 (2020)
        [HAL open access]
        DOI: 10.1039/D0RA05519K in open access
        2019  
      1. Alkylation of uracil and thymine in the gas phase through interaction with alkylmercury compounds.
        J-Y. Salpin, V. Haldys, L. Latrous, J-C. Guillemin, J. Tortajada, E. Léon, O. Mó, M. Yáñez, M. Merced Montero-Campillo.
        International Journal of Mass Spectrometry  436, 153-165 (2019)
        [HAL open access]
        DOI:10.1016/j.ijms.2018.12.003
      2. Combined experimental and theoretical survey of the gas-phase
        reactions of serine-Ca2+ adducts.
        A. M. Lamsabhi, O. Mo, M. Yanez, J-Y. Salpin.
        Journal of Physical Chemistry A 123, 6241-6250 (2019)
        [HAL open access]
        DOI:10.1021/acs.jpca.9b03977
        2018  
      1. Topologic and electronic density driven generation of alkali cation complexes.
        H. Boufroura, S. Poyer, A. Gaucher, C. Huin, J-Y. Salpin, G. Clavier, D. Prim
        Chemistry. A European Journal  24, 8656-8663 (2018)
        [HAL open access]
        DOI :10.1002/chem.201800707
      2. Interactions of dimethyltin(IV) with uracil as studied in the gas phase
        J-Y. Salpin, L. Latrous, V. Haldys, A. M. Lamsabhi
        Journal of Physical Chemistry A  122, 992-1003 (2018)
        [HAL open access]
        DOI: 10.1021/acs.jpca.7b11510
      3. Structures of [M(Ura-H)(Ura)]+ and [M(Ura-H)(H2O)n]+ (M = Cu, Zn, Pb; n = 1 – 3) Complexes in the Gas Phase by IRMPD Spectroscopy in the Fingerprint Region and Theoretical Studies.
        B. Power, V. Haldys, J-Y. Salpin, T. Fridgen.
        International Journal of Mass Spectrometry 429, 56-65 (2018).
        [HAL open access]
        DOI:10.1016/j.ijms.2017.05.003
      4. Protonation of Methyl-Uracils in The Gas Phase: The Particular Case of 3-Methyl-uracil
        J-Y. Salpin, V. Haldys, V. Steinmetz, E. Léon, M. Yáñez, M. Merced Montero-Campillo
        International Journal of Mass Spectrometry 429, 47-55 (2018).
        [HAL open access]
        DOI:10.1016/j.ijms.2017.05.004
        2017  
      1. Isomer separation and effect of the polymerization degree on the gas-phase structure of chondroitin sulfate oligosaccharides analyzed by ion mobility-tandem mass spectrometry.
        S. Poyer, C. Lopin-Bon, J-C. Jacquinet, J-Y. Salpin,R Daniel.
        Rapid Communications in Mass Spectrometry  31, 2003-2010 (2017)
        [HAL open access]
        DOI:10.1002/rcm.7987
      2. Conformational Dynamics in Ion Mobility Data
        S. Poyer, C. Combi-Zerbino, C. M. Choi, L. MacAleese, C. Déo, N. Bogliotti, J. Xie, J-Y. Salpin, P. Dugourd, F. Chirot
        Analytical Chemistry  89, 4230-4237 (2017)
        [HAL open access]
        DOI: 10.1021/acs.analchem.7b00281
      3. Identification of acylation products in SHAPE Chemistry
        C. Lin, S. Poyer, L. Zargarian, J-Y. Salpin, P. Fossé, O. Mauffret, J. Xie
        Bioorganic & Medicinal Chemistry Letters  27, 2506-2509 (2017)
        [HAL open access]
        DOI:10.1016/j.bmcl.2017.03.096
      4. Undervalued N3-coordination revealed in the cisplatin complex with 2'-Deoxyadenosine-5'-monophosphate
        B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
        Inorganic Chemistry 56, 8793-8801 (2017)
        [HAL open access]
        DOI: 10.1021/acs.inorgchem.7b00570
      5. Characterization of protonated model disaccharides from tandem mass spectrometry and chemical dynamics simulations
        E. Rossich-Molina, A. Eizaguirre, V. Haldys, D. Urban, G. Doisneau, Y. Bourdreux, J-M. Beau, J-Y. Salpin, R. Spezia
        ChemPhysChem  18, 2812-2823 (2017)
        DOI:10.1002/cphc.201700202 in open access
        2016  
      1. Structures of [M(Ura-H)(H2O)n]+ (M=Mg, Ca, Sr, Ba ; n=1–3) complexes in the gas phase by IRMPD spectroscopy and theoretical studies
        B. Power, V. Haldys, J-Y. Salpin, T. D. Fridgen
        International Journal of Mass Spectrometry  51, 236-244 (2016)
        [HAL open access]
        DOI:10.1002/jms.3739
      2. On the gas phase fragmentation of protonated uracil : a statistical perspective
        E. Rossich-Molina, J-Y. Salpin, R. Spezia, E. Martinez-Nunez
        Physical Chemistry Chemical Physics  16, 14127-14138 (2016)
        [HAL open access soon]
        DOI:10.1039/C6CP01657J
      3. Gas-phase interactions of organotins compounds with cysteine
        L. Latrous, J-Y. Salpin, V. Haldys, E. Léon, C. Correia, A. M. Lamsabhi
        Journal of Mass Spectrometry  51, 1006-1015 (2016)
        [HAL open access]
        DOI:10.1002/jms.3812
        2015  
      1. Structures of bare and singly hydrated [M(Ura-H)(Ura)]+ (M=Mg, Ca, Sr, Ba) complexes in the gas phase by IRMPD spectroscopy in the fingerprint region
        B. Power, V. Haldys, J-Y. Salpin, T. Fridgen
        International Journal of Mass Spectrometry  378, 328-335 (2015)
        [HAL open access]
        DOI:10.1016/j.ijms.2014.10.002
      2. Interaction of cisplatin with dGMP : a combined IRMPD and theoretical study
        B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
        Inorganic Chemistry          54, 3513-3522 (2015)
        [HAL open access]
        DOI:10.1021/acs.inorgchem.5b00070
      3. Effects of Calcium complexation on Heparin-like disaccharide. A combined theoretical, MS/MS and UV experiments
        D. Ortiz, Q. Enjalbert, L. MacAleese, P. Dugourd, J-Y. Salpin
        Rapid Communication in Mass Spectrometry         29, 1135-1144 (2015)
        [HAL open access]
        DOI:10.1002/rcm.7204
      4. Elucidating collision induced dissociation products and reaction mechanisms of protonated uracil by coupling chemical dynamics simulations with tandem mass spectrometry experiments
        E. Rossich-Molina, D. Ortiz, J-Y. Salpin, R. Spezia
        Journal of Mass Spectrometry  50, 1340-1351 (2015)
        [HAL open access]
        DOI:10.1002/jms.3704
      5. Structure of protonated thymidine characterized by InfraRed Multiple Photon Dissociation and quantum calculations
        J-Y. Salpin, D. Scuderi
        Rapid Communication in Mass Spectrometry  29, 1898-1904 (2015)
        [HAL open access]
        DOI:10.1002/rcm.7296
        2014  
      1. Galactose 6-sulfate collision induced dissociation from QM+MM chemical dynamics simulations and ESI-MS/MS experiments
        D. Ortiz, J-Y. Salpin, K. Song, R. Spezia
        International Journal of Mass Spectrometry          358, 25-35 (2014)
        [HAL open access soon]
        DOI:10.1016/j.ijms.2013.11.002
      2. Structure of the Pb2+–deprotonated dGMP complex in the gas phase : a combined MS-MS/IRMPD spectroscopy/ion mobility study
        J-Y. Salpin, L. MacAleese, F. Chirot, P. Dugourd
        Physical Chemistry Chemical Physics         16, 14127-14138 (2014)
        [HAL open access]
        DOI:10.1039/C4CP00163J
      3. Gas-phase interactions between Lead(II) ions and Cytosine as probed by MS/MS and IRMPD spectroscopy
        J-Y. Salpin, V. Haldys, S. Guillaumont, J. Tortajada, M. Hurtado, A.M. Lamsabhi
        ChemPhysChem         15, 2959-2971 (2014)
        [HAL open access]
        DOI:10.1002/cphc.201402369
        2013  
      1. Reactivity of Lanthanoid Mono-Cations with Ammonia : a Combined Inductively Coupled Plasma Mass Spectrometry and Computational Investigation
        A. Quemet, P. Vitorge, A. Cimas, S. Liu, J-Y. Salpin, C. Marsden, J. Tortajada, L. Gagliardi, R. Spezia, M.-P. Gaigeot, R. Brennetot
        International Journal of Mass Spectrometry         334, 27-37 (2013)
        [HAL open access]
        DOI:10.1016/j.ijms.2012.10.005
      2. Gas-phase collision induced dissociation mechanisms of peptides: Theoretical and experimental study of N-formylalanylamide fragmentation
        D. Ortiz, R. Spezia, P. Martin-Gago, A. Riera, K. Song, J-Y. Salpin
        International Journal of Mass Spectrometry  335, 33-44 (2013)
        [HAL open access]
        DOI:10.1016/j.ijms.2012.11.001
      3. Interaction of cisplatin with adenine and guanine : a combined IRMPD, MS/MS and theoretical study
        B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
        Journal of the American Chemical Society          135, 1445-1455 (2013)
        [HAL open access]
        DOI:10.1021/ja309857d
      4. Unimolecular reactivity of the [urea-Sr]2+ complex, a metastable dication in the gas phase. An experimental and theoretical perspective
        A. Eizaguirre, O. Mó, M. Yáñez, J. Tortajada, J-Y. Salpin
        Journal of Physical Chemistry B          117, 2088-2095 (2013)
        [HAL open access]
        DOI:10.1021/jp312466t
      5. Gas-phase interactions of organotin compounds with glycine
        L. Latrous, J. Tortajada, V. Haldys, E. Léon, C. Correia, J-Y. Salpin
        Journal of Mass Spectrometry  48, 795-806 (2013)
        [HAL open access]
        DOI:10.1002/jms.3223
      6. Modeling Interactions between an Amino Acid and a Metal Dication : Cysteine–Calcium(II) Reactions in the Gas Phase
        M. Hurtado, M. Monte, A. M. Lamsabhi, O. Mó, M. Yáñez, J-Y. Salpin
        ChemPlusChem 78, 1124-1133 (2013)
        [HAL open access]
        DOI:10.1002/cplu.20130016
      7. Correction to interaction of cisplatin with adenine and guanine : a combined IRMPD, MS/MS and theoretical study
        B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
        Journal of the American Chemical Society  135, 10877 (2013)
        DOI: 10.1021/ja405235n
        2012  
      1. Modelling peptide-metal dication interactions : Formamide-Ca2+ reactions in the Gas Phase
        A. Eizaguirre, O. Mó, M. Yáñez, J-Y. Salpin, J. Tortajada
        Organic and Biomolecular Chemistry  10, 11752-11761 (2012)
        [HAL open access]
        DOI:10.1039/C2OB26166A
      2. How Can f-Block Monocations Behave as Monocations of d-Block Transition Metals ?
        A. Quemet, R. Brennetot, J-Y. Salpin, A. Cimas, C. Marsden, J. tortajada, P. Vitorge
        European Journal of Inorganic Chemistry, 3551-3555 (2012)
        [HAL open access]
        DOI:10.1002/ejic.201200455
      3. Collision Induced Dissociation of Doubly-charged Ions : Coulomb Explosion vs Neutral Loss in [Ca(urea)]2+ Gas Phase Unimolecular Reactivity via Chemical Dynamics Simulations
        R. Spezia, A. Cimas, M-P. Gaigeot, J-Y. Salpin, K. Song, W. L. Hase
        PhysChemChemPhys 14, 11724-11736 (2012)
        [HAL open access soon]
        DOI:10.1039/c2cp41379e
      4. Gas-phase basicities of polyfunctional molecules. Part 2 : saturated basic sites
        G. Bouchoux, J.-Y. Salpin
        Mass Spectrometry Reviews  31, 353-390 (2012)
        [HAL open access]
        DOI:10.1002/mas.20343
        2011  
      1. Modeling the interactions between peptide functions and Sr2+ : Formamide-Sr2+ reactions in the Gas Phase
        A. Eizaguirre, O. Mó, M. Yáñez, J.-Y. Salpin
        PhysChemChemPhys  13, 18409-18417 (2011)
        [HAL open access]
        DOI:10.1039/c1cp21578g
      2. Direct evidence for tautomerization of the uracil moiety within the Pb2+/Uridine-5’-monophosphate complex : a combined tandem mass spectrometry and IRMPD study
        J.-Y. Salpin, S. Guillaumont, D. Ortiz, J. Tortajada, P. Maître
        Inorganic Chemistry  50, 7769-7778 (2011)
        [HAL open access]
        DOI:10.1021/ic200918q
      3. Unimolecular reactivity upon collision of Uracil-Ca2+ complexes in the gas phase : comparison with uracil-M+ (M=H, alkali metals) and uracil-M2+ (M=Cu, Pb) systems
        C. Trujillo, A. M. Lamsabhi, O. Mó, M. Yáñez, J.-Y. Salpin
        International Journal of Mass spectrometry  306, 27-36 (2011)
        [HAL open access]
        DOI:10.1016/j.ijms.2011.05.018
      4. Structure of Pb2+/dCMP and Pb2+/CMP complexes as characterized by tandem mass spectrometry and IRMPD spectroscopy
        J-Y Salpin, L. Gamiette, J. Tortajada, T. Besson, P. Maitre
        International Journal of Mass Spectrometry  304, 154-164 (2011)
        [HAL open access]
        DOI:10.1016/j.ijms.2010.07.011
        2010  
      1. Negative-ion photoelectron spectroscopy of the copper-aspartic acid anion and its hydrated complexes
        X. Li, H. Wang, K. H. Bowen, A. Martínez, J.-Y. Salpin, J.-P. Schermann
        Journal of Chemical Physics  133, 084303-084303-6 (2010)
        [HAL open access]
        DOI:10.1063/1.3466923
      2. Book chapter
        Ca2+ reactivity in the gas phase. Bonding, catalytic effects and coulomb explosions
        Inés Corral, Cristina Trujillo, Jean-Yves Salpin, Manuel Yáñez
        Kinetics and Dynamics : from nano- to bio-scale Series : Challenges and Advances in Computational Chemistry and Physics
        Editors :Piotr Paneth and Agnieszka Dybala-Defratyka
        Publisher : Springer
        Paru
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