JEAN-YVES SALPIN

JEAN-YVES SALPIN
Poste Actuel
Directeur de Recherche (DR1) CNRS, Institut de Chimie
Activités de recherche
- Etude des interactions entre des cations métalliques toxiques et des molécules organiques et biologiques polyfonctionnelles par spectrométrie de masse et calculs quantiques.
- Thermochimie en phase gazeuse de molécules biologiques
- Structure d’ions gazeux par spectroscopie infra-rouge de type IRMPD.
- Etude de récepteurs anioniques et cationiques
Outils
- Spectrométrie de masse : Triple-quadripôle, piège ionique et instrument hybride de type QqTOF ou Orbitrap, équipés de source de type electrospray (ESI) et nano-ESI.
- Spectroscopie d'action (IRMPD, UVPD) , mobilité ionique
- Calculs de Chimie Quantique.
- Institut Lumière-Matière (ILM) – UMR 5536
- Laboratoire de Chimie-Physique (LCP) - UMR 8000
- Institut Louis Lavoisier (ILV) – UMR 8182
- Ecole Nationale Supérieure de Chimie de Rennes – UMR 6226
- Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires - UMR 8531
- Université Autonoma de Madrid (Espagne)
- Université de Tunis El Manar (Tunisie)
- Université « La Sapienza » de Rome (Italie)
- West Virginia University (USA)
- Memorial University of Newfoundland (Canada)
- Membre du Conseil Scientifique de l'INC (CNRS)
- Membre du Comité de Pilotage du LabEx Charm3at, coordinateur de l’axe D (Stratégies multi-échelles et sondes multifonctionnelles)
- Membre du bureau de la Graduate School (GS) Chimie de l’Université Paris-Saclay
- Membre du GT science ouverte de l'Université Paris-Saclay
- Membre du bureau du GDR "Imagerie par spectrométrie de masse" (MSI-2125)
- Membre du Comité de direction de la fédération de Recherche "Chimie-Physique de Paris Saclay" (FR 3510)
- Expert scientifique auprès du FNRS (Belgique), FNSNF (Suisse), ANR
- Correspondant documentaire auprès de BiblioSciences et Couperin
- Cours et Travaux dirigés d’analyse structurale en licence et Master à l’Université d’Evry Val d’Essonne et Université de Paris-Saclay.
- Enseignement en Formation Permanente.
A ce jour, l'intégralité de mes publications est parue dans des revues à comité de lecture nécessitant un abonnement payant auprès dans principaux éditeurs de revues scientifiques (Elsevier, Springer, ACS, Wiley, etc...). Dans le contexte du basculement de la politique de publication scientifique vers un modèle open access, et afin de rendre accessible gratuitement à tous les chercheurs mes travaux publiés, j'ai opté à ce jour pour une voie green open access, consistant à déposer sur la base HAL, les manuscrits révisés et acceptés de mes publications. Les documents correspondant aux publications les plus récentes, sont disponibles en cliquant sur les liens [HAL open access]
To date, all my publications have appeared in peer-reviewed journals requiring a paid subscription from leading publishers of scientific journals (Elsevier, Springer, ACS, Wiley, etc ...). In the context of the switchover from the scientific publication policy towards an open access model, and in order to make my published works available to all researchers free of charge, I have opted for a green open access, by depositing onto the HAL database, the revised and accepted manuscripts of my publications. The documents corresponding to the most recent publications are available by clicking on the links [HAL open access]
- Chloride binding modulated by anion receptors bearing tetrazine and urea
R. Plais, G. Gouarin, A. Bournier, O. Zayene, V. Mussard, F. Bourdreux, J. Marrot, A. Brosseau, A. Gaucher, G. Clavier, J-Y. Salpin, D. Prim
ChemPhysChem, 24, e202200524 (2023)
[HAL open access]
DOI:10.1002/cphc.202200524
- Dereplication of acetogenins from Annona muricata by combining tandem mass spectrometry after lithium and copper postcolumn cationization and molecular networks
S. Poyer, L. Laboureur, T. Hebra, N. Elie, R. G. van der Rest, J-Y. Salpin, P. Champy, D. Touboul
Journal of the American Society for Mass Spectrometry, 33, 627-634 (2022)
[HAL open access]
DOI:10.1021/jasms.1c00303 - Open questions on toxic heavy metals Cd, Hg and Pb binding small components of DNA and nucleobases. Are there any predictable trends?
A. Pérez-Barcia, M. Merced Montero Campillo, A. M. Lamsabhi, J-Y. Salpin, M. Yáñez
Physical Chemistry Chemical Physics, 24, 20624-20637 (2022)
[HAL open access]
DOI:10.1039/D2CP02459D - Anion- interaction for the molecular recognition of anions (2000-2022) : focus on cooperativity with Hydrogen Bonding
R. Plais, G. Clavier, J-Y. Salpin, A. Gaucher, D. Prim
European Journal of Organic Chemistry, e202201281
[HAL open access]
DOI:10.1002/ejoc.202201281
- Design and Properties Investigation on a Five-Interaction-based Fluorescent Anion Receptor Clip
R. Plais, H. Boufroura, G. Gouarin, A. Gaucher, V. Haldys, A. Brosseau, G. Clavier, J-Y. Salpin, D. Prim
RSC Advances 11, 9476-9487 (2021)
INC: en direct des laboratoires
[HAL open access]
DOI:10.1039/D1RA00630D - Discrimination of sulfated isomers of chondroitine sulfate disaccharides by HILIC-MS
S. Poyer, I. Seffouh, C. Lopin-Bon, J-C. Jacquinet, J. L. Neira, J-Y. Salpin, R. Daniel
Analytical and Bionanalytical Chemistry 413, 7107-7117 (2021)
[HAL open access]
DOI:10.1007/s00216-021-03679-9
- Intertwined detection and recognition roles of tetrazine in synergistic anion-π and H-bond based anion receptor.
R. Plais, G. Gouarin, A. Gaucher, V. Haldys, A. Brosseau, G. Clavier, J-Y. Salpin, D. Prim
ChemPhysChem 21, 1249-1257 (2020)
[HAL open access]
DOI:10.1002/cphc.202000289 - Kinetic study of azobenzene E/Z isomerization using ion mobility-mass spectrometry and liquid chromatography-UV detection
S. Poyer, C. M. Choi, C. Deo, N. Bogliotti, J. Xie, P. Dugourd, F. Chirot, J-Y. Salpin
Analyst 145, 4012-4020 (2020)
[HAL open access]
DOI: 10.1039/D0AN00048E - Insights into Cisplatin Binding to Uracil and Thiouracils from IRMPD Spectroscopy and Tandem Mass Spectrometry
D. Corinti, M. E. Crestoni, B. Chiavarino, S. Fornarini, D. Scuderi, J-Y. Salpin
Journal of the American Society for Mass Spectrometry 31, 946-960 (2020)
[HAL open access]
DOI: 10.1021/jasms.0c00006# - Helically-shaped cation receptor: design, synthesis, characterisation and first application to ion transport
H. Boufroura, R. Plais, S. Poyer, A. Gaucher, J. Marrot, G. Clavier, F-X. Legrand, C. Huin, P. Guégan, D. Prim, J-Y. Salpin
RSC Advances 10, 31670-31679 (2020)
[HAL open access]
DOI: 10.1039/D0RA05519K in open access
- Alkylation of uracil and thymine in the gas phase through interaction with alkylmercury compounds.
J-Y. Salpin, V. Haldys, L. Latrous, J-C. Guillemin, J. Tortajada, E. Léon, O. Mó, M. Yáñez, M. Merced Montero-Campillo.
International Journal of Mass Spectrometry 436, 153-165 (2019)
[HAL open access]
DOI:10.1016/j.ijms.2018.12.003 - Combined experimental and theoretical survey of the gas-phase
reactions of serine-Ca2+ adducts.
A. M. Lamsabhi, O. Mo, M. Yanez, J-Y. Salpin.
Journal of Physical Chemistry A 123, 6241-6250 (2019)
[HAL open access]
DOI:10.1021/acs.jpca.9b03977
- Topologic and electronic density driven generation of alkali cation complexes.
H. Boufroura, S. Poyer, A. Gaucher, C. Huin, J-Y. Salpin, G. Clavier, D. Prim
Chemistry. A European Journal 24, 8656-8663 (2018)
[HAL open access]
DOI :10.1002/chem.201800707 - Interactions of dimethyltin(IV) with uracil as studied in the gas phase
J-Y. Salpin, L. Latrous, V. Haldys, A. M. Lamsabhi
Journal of Physical Chemistry A 122, 992-1003 (2018)
[HAL open access]
DOI: 10.1021/acs.jpca.7b11510 - Structures of [M(Ura-H)(Ura)]+ and [M(Ura-H)(H2O)n]+ (M = Cu, Zn, Pb; n = 1 – 3) Complexes in the Gas Phase by IRMPD Spectroscopy in the Fingerprint Region and Theoretical Studies.
B. Power, V. Haldys, J-Y. Salpin, T. Fridgen.
International Journal of Mass Spectrometry 429, 56-65 (2018).
[HAL open access]
DOI:10.1016/j.ijms.2017.05.003 - Protonation of Methyl-Uracils in The Gas Phase: The Particular Case of 3-Methyl-uracil
J-Y. Salpin, V. Haldys, V. Steinmetz, E. Léon, M. Yáñez, M. Merced Montero-Campillo
International Journal of Mass Spectrometry 429, 47-55 (2018).
[HAL open access]
DOI:10.1016/j.ijms.2017.05.004
- Isomer separation and effect of the polymerization degree on the gas-phase structure of chondroitin sulfate oligosaccharides analyzed by ion mobility-tandem mass spectrometry.
S. Poyer, C. Lopin-Bon, J-C. Jacquinet, J-Y. Salpin,R Daniel.
Rapid Communications in Mass Spectrometry 31, 2003-2010 (2017)
[HAL open access]
DOI:10.1002/rcm.7987 - Conformational Dynamics in Ion Mobility Data
S. Poyer, C. Combi-Zerbino, C. M. Choi, L. MacAleese, C. Déo, N. Bogliotti, J. Xie, J-Y. Salpin, P. Dugourd, F. Chirot
Analytical Chemistry 89, 4230-4237 (2017)
[HAL open access]
DOI: 10.1021/acs.analchem.7b00281 - Identification of acylation products in SHAPE Chemistry
C. Lin, S. Poyer, L. Zargarian, J-Y. Salpin, P. Fossé, O. Mauffret, J. Xie
Bioorganic & Medicinal Chemistry Letters 27, 2506-2509 (2017)
[HAL open access]
DOI:10.1016/j.bmcl.2017.03.096 - Undervalued N3-coordination revealed in the cisplatin complex with 2'-Deoxyadenosine-5'-monophosphate
B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
Inorganic Chemistry 56, 8793-8801 (2017)
[HAL open access]
DOI: 10.1021/acs.inorgchem.7b00570 - Characterization of protonated model disaccharides from tandem mass spectrometry and chemical dynamics simulations
E. Rossich-Molina, A. Eizaguirre, V. Haldys, D. Urban, G. Doisneau, Y. Bourdreux, J-M. Beau, J-Y. Salpin, R. Spezia
ChemPhysChem 18, 2812-2823 (2017)
[HAL open access]
DOI:10.1002/cphc.201700202 in open access
- Structures of [M(Ura-H)(H2O)n]+ (M=Mg, Ca, Sr, Ba ; n=1–3) complexes in the gas phase by IRMPD spectroscopy and theoretical studies
B. Power, V. Haldys, J-Y. Salpin, T. D. Fridgen
International Journal of Mass Spectrometry 51, 236-244 (2016)
[HAL open access]
DOI:10.1002/jms.3739 - On the gas phase fragmentation of protonated uracil : a statistical perspective
E. Rossich-Molina, J-Y. Salpin, R. Spezia, E. Martinez-Nunez
Physical Chemistry Chemical Physics 16, 14127-14138 (2016)
[HAL open access soon]
DOI:10.1039/C6CP01657J - Gas-phase interactions of organotins compounds with cysteine
L. Latrous, J-Y. Salpin, V. Haldys, E. Léon, C. Correia, A. M. Lamsabhi
Journal of Mass Spectrometry 51, 1006-1015 (2016)
[HAL open access]
DOI:10.1002/jms.3812
- Structures of bare and singly hydrated [M(Ura-H)(Ura)]+ (M=Mg, Ca, Sr, Ba) complexes in the gas phase by IRMPD spectroscopy in the fingerprint region
B. Power, V. Haldys, J-Y. Salpin, T. Fridgen
International Journal of Mass Spectrometry 378, 328-335 (2015)
[HAL open access]
DOI:10.1016/j.ijms.2014.10.002 - Interaction of cisplatin with dGMP : a combined IRMPD and theoretical study
B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
Inorganic Chemistry 54, 3513-3522 (2015)
[HAL open access]
DOI:10.1021/acs.inorgchem.5b00070 - Effects of Calcium complexation on Heparin-like disaccharide. A combined theoretical, MS/MS and UV experiments
D. Ortiz, Q. Enjalbert, L. MacAleese, P. Dugourd, J-Y. Salpin
Rapid Communication in Mass Spectrometry 29, 1135-1144 (2015)
[HAL open access]
DOI:10.1002/rcm.7204 - Elucidating collision induced dissociation products and reaction mechanisms of protonated uracil by coupling chemical dynamics simulations with tandem mass spectrometry experiments
E. Rossich-Molina, D. Ortiz, J-Y. Salpin, R. Spezia
Journal of Mass Spectrometry 50, 1340-1351 (2015)
[HAL open access]
DOI:10.1002/jms.3704 - Structure of protonated thymidine characterized by InfraRed Multiple Photon Dissociation and quantum calculations
J-Y. Salpin, D. Scuderi
Rapid Communication in Mass Spectrometry 29, 1898-1904 (2015)
[HAL open access]
DOI:10.1002/rcm.7296
- Galactose 6-sulfate collision induced dissociation from QM+MM chemical dynamics simulations and ESI-MS/MS experiments
D. Ortiz, J-Y. Salpin, K. Song, R. Spezia
International Journal of Mass Spectrometry 358, 25-35 (2014)
[HAL open access soon]
DOI:10.1016/j.ijms.2013.11.002 - Structure of the Pb2+–deprotonated dGMP complex in the gas phase : a combined MS-MS/IRMPD spectroscopy/ion mobility study
J-Y. Salpin, L. MacAleese, F. Chirot, P. Dugourd
Physical Chemistry Chemical Physics 16, 14127-14138 (2014)
[HAL open access]
DOI:10.1039/C4CP00163J - Gas-phase interactions between Lead(II) ions and Cytosine as probed by MS/MS and IRMPD spectroscopy
J-Y. Salpin, V. Haldys, S. Guillaumont, J. Tortajada, M. Hurtado, A.M. Lamsabhi
ChemPhysChem 15, 2959-2971 (2014)
[HAL open access]
DOI:10.1002/cphc.201402369
- Reactivity of Lanthanoid Mono-Cations with Ammonia : a Combined Inductively Coupled Plasma Mass Spectrometry and Computational Investigation
A. Quemet, P. Vitorge, A. Cimas, S. Liu, J-Y. Salpin, C. Marsden, J. Tortajada, L. Gagliardi, R. Spezia, M.-P. Gaigeot, R. Brennetot
International Journal of Mass Spectrometry 334, 27-37 (2013)
[HAL open access]
DOI:10.1016/j.ijms.2012.10.005 - Gas-phase collision induced dissociation mechanisms of peptides: Theoretical and experimental study of N-formylalanylamide fragmentation
D. Ortiz, R. Spezia, P. Martin-Gago, A. Riera, K. Song, J-Y. Salpin
International Journal of Mass Spectrometry 335, 33-44 (2013)
[HAL open access]
DOI:10.1016/j.ijms.2012.11.001 - Interaction of cisplatin with adenine and guanine : a combined IRMPD, MS/MS and theoretical study
B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
Journal of the American Chemical Society 135, 1445-1455 (2013)
[HAL open access]
DOI:10.1021/ja309857d - Unimolecular reactivity of the [urea-Sr]2+ complex, a metastable dication in the gas phase. An experimental and theoretical perspective
A. Eizaguirre, O. Mó, M. Yáñez, J. Tortajada, J-Y. Salpin
Journal of Physical Chemistry B 117, 2088-2095 (2013)
[HAL open access]
DOI:10.1021/jp312466t - Gas-phase interactions of organotin compounds with glycine
L. Latrous, J. Tortajada, V. Haldys, E. Léon, C. Correia, J-Y. Salpin
Journal of Mass Spectrometry 48, 795-806 (2013)
[HAL open access]
DOI:10.1002/jms.3223 - Modeling Interactions between an Amino Acid and a Metal Dication : Cysteine–Calcium(II) Reactions in the Gas Phase
M. Hurtado, M. Monte, A. M. Lamsabhi, O. Mó, M. Yáñez, J-Y. Salpin
ChemPlusChem 78, 1124-1133 (2013)
[HAL open access]
DOI:10.1002/cplu.20130016 - Correction to interaction of cisplatin with adenine and guanine : a combined IRMPD, MS/MS and theoretical study
B. Chiavarino, M.-E. Crestoni, S. Fornarini, D. Scuderi, J-Y. Salpin
Journal of the American Chemical Society 135, 10877 (2013)
DOI: 10.1021/ja405235n
- Modelling peptide-metal dication interactions : Formamide-Ca2+ reactions in the Gas Phase
A. Eizaguirre, O. Mó, M. Yáñez, J-Y. Salpin, J. Tortajada
Organic and Biomolecular Chemistry 10, 11752-11761 (2012)
[HAL open access]
DOI:10.1039/C2OB26166A - How Can f-Block Monocations Behave as Monocations of d-Block Transition Metals ?
A. Quemet, R. Brennetot, J-Y. Salpin, A. Cimas, C. Marsden, J. tortajada, P. Vitorge
European Journal of Inorganic Chemistry, 3551-3555 (2012)
[HAL open access]
DOI:10.1002/ejic.201200455 - Collision Induced Dissociation of Doubly-charged Ions : Coulomb Explosion vs Neutral Loss in [Ca(urea)]2+ Gas Phase Unimolecular Reactivity via Chemical Dynamics Simulations
R. Spezia, A. Cimas, M-P. Gaigeot, J-Y. Salpin, K. Song, W. L. Hase
PhysChemChemPhys 14, 11724-11736 (2012)
[HAL open access soon]
DOI:10.1039/c2cp41379e - Gas-phase basicities of polyfunctional molecules. Part 2 : saturated basic sites
G. Bouchoux, J.-Y. Salpin
Mass Spectrometry Reviews 31, 353-390 (2012)
[HAL open access]
DOI:10.1002/mas.20343
- Modeling the interactions between peptide functions and Sr2+ : Formamide-Sr2+ reactions in the Gas Phase
A. Eizaguirre, O. Mó, M. Yáñez, J.-Y. Salpin
PhysChemChemPhys 13, 18409-18417 (2011)
[HAL open access]
DOI:10.1039/c1cp21578g - Direct evidence for tautomerization of the uracil moiety within the Pb2+/Uridine-5’-monophosphate complex : a combined tandem mass spectrometry and IRMPD study
J.-Y. Salpin, S. Guillaumont, D. Ortiz, J. Tortajada, P. Maître
Inorganic Chemistry 50, 7769-7778 (2011)
[HAL open access]
DOI:10.1021/ic200918q - Unimolecular reactivity upon collision of Uracil-Ca2+ complexes in the gas phase : comparison with uracil-M+ (M=H, alkali metals) and uracil-M2+ (M=Cu, Pb) systems
C. Trujillo, A. M. Lamsabhi, O. Mó, M. Yáñez, J.-Y. Salpin
International Journal of Mass spectrometry 306, 27-36 (2011)
[HAL open access]
DOI:10.1016/j.ijms.2011.05.018 - Structure of Pb2+/dCMP and Pb2+/CMP complexes as characterized by tandem mass spectrometry and IRMPD spectroscopy
J-Y Salpin, L. Gamiette, J. Tortajada, T. Besson, P. Maitre
International Journal of Mass Spectrometry 304, 154-164 (2011)
[HAL open access]
DOI:10.1016/j.ijms.2010.07.011
- Negative-ion photoelectron spectroscopy of the copper-aspartic acid anion and its hydrated complexes
X. Li, H. Wang, K. H. Bowen, A. Martínez, J.-Y. Salpin, J.-P. Schermann
Journal of Chemical Physics 133, 084303-084303-6 (2010)
[HAL open access]
DOI:10.1063/1.3466923 - Book chapter
Ca2+ reactivity in the gas phase. Bonding, catalytic effects and coulomb explosions
Inés Corral, Cristina Trujillo, Jean-Yves Salpin, Manuel Yáñez
Kinetics and Dynamics : from nano- to bio-scale Series : Challenges and Advances in Computational Chemistry and Physics
Editors :Piotr Paneth and Agnieszka Dybala-Defratyka
Publisher : Springer
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